m8891 2023年8月24日 — M8891 is a novel orally bioavailable, potent, selective, reversible MetAP2 inhibitor with antiangiogenic and antitumor activity in preclinical studies.

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由 MA Carducci 著作 2023 被引用 9 次 M8891 is a novel orally bioavailable potent selective reversible MetAP2 inhibitor with antiangiogenic and antitumor activity in preclinical studies A proprietary orally available inhibitor of methionine aminopeptidase 2 MetAP2 which cleaves the amino terminal methionine residue from nascent proteins 由 F Lignet 著作 2023 被引用 2 次 M8891 is a selective and reversible inhibitor of methionine aminopeptidase 2 MetAP2 We describe translational research to define the target pharmacokinetics  The purpose of this study was to determine the maximum tolerated dose MTD safety tolerability Pharmacokinetic PK pharmacodynamic and clinical activity  由 M Friese Hamim 著作 2024 被引用 2 次 M8891 is a potent selective reversible small molecule inhibitor blocking the growth of human endothelial cells and differentially inhibiting cancer cell 

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4.9 out of 5 stars
525753 global ratings

Top reviews from the Thailand

  • pro_9890
    5.0 out of 5 starsVerified Purchase
    Definition of methionine aminopeptidase 2 inhibitor M8891
    Reviewed in the Thailand on July 6, 2025
    Comment: M8891 is an inhibitor of methionine aminopeptidase-2 (MetAP-2) [1]. It was developed for anti-tumour potential. Click here for help ...
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  • lucky4869
    1.0 out of 5 starsVerified Purchase
    M8891 | MetAP-2 Inhibitor
    Reviewed in the Thailand on July 17, 2025
    2023年8月24日 — M8891 is a novel orally bioavailable, potent, selective, reversible MetAP2 inhibitor with antiangiogenic and antitumor activity in preclinical studies.
    One person found this helpful
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  • pro_4824
    1.0 out of 5 stars
    Definition of methionine aminopeptidase 2 inhibitor M8891
    Reviewed in the Thailand on June 25, 2025
    M8891 is a potent and orally active methionine aminopeptidase 2 inhibitor with potential antiangiogenic and antineoplastic activities.
    15 people found this helpful
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